Analyst ratings
17 analysts have weighed in: a Strong Buy consensus: 17 buy calls against 0 sell, with an average 12-month price target of $103.93.
NASDAQ: SYRE · Biotechnology
Over the past week, Spyre Therapeutics (SYRE) racked up 6 mentions across Reddit, X and news, and the read is an Adanos Hold. That is too little tracked discussion to read a direction from, so the signal stays neutral. Wall Street is more constructive, with 17 of 17 analysts rating SYRE a buy.
Tracked discussion on SYRE is too thin this week to read a direction from, which is why it reads as a Hold.
Wall Street’s 100% buy share sits next to a crowd that ranges from Reddit at 0% to News at 50%. No other tracker puts the two side by side.
17 analysts have weighed in: a Strong Buy consensus: 17 buy calls against 0 sell, with an average 12-month price target of $103.93.
The Adanos signal blends each source’s bullish ratio, source breadth, buzz intensity and 3-day momentum. This week SYRE carries too few tracked mentions to weigh any of them, so the read is Hold rather than a clear buy or sell.
Analysts sit 72 points above the crowd average of 28%, the professionals are more constructive than retail. The split is inside the crowd: News reads 50% bullish while Reddit sits at 0%, a 50-point spread that single-source trackers miss.
Over the 30-day window, Spyre Therapeutics (SYRE) buzz held subdued around 30.8 while the price drifted up 13.3% across the period. The chart tracks how social and news attention moved against end-of-day price. Average daily trading volume across the displayed trading days is 1.2M shares. Updated Jul 27, 2026. Over the last 7 trading days, SYRE gained 8.5%. Buzz activity in the recent week averaged 32.3 and was relatively stable, swinging between 24.7 and 39.4. Recent volume is running below the 30-day average, pointing to quieter participation. Daily crowd sentiment leaned bullish on 7 of the 11 days with directional mentions, shown as the green, grey and red breakdown bars below the chart.
Buzz, bullish share, the loudest item and the positive / neutral / negative split for every tracked source over the last 7 days.
No Polymarket data for this stock this week.
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View WidgetsThis week’s sentiment from Adanos, with fundamentals and analyst consensus. A quick-reference snapshot for Jul 27, 2026.
Adanos will not call Spyre Therapeutics (SYRE) either way right now. The last 7 days carry 6 tracked mentions across 3 sources, under the 10-mention floor, so the signal sits at a neutral hold with 40/100 conviction. This is a sentiment-based reading, not financial advice.
Reddit discussion around Spyre Therapeutics (SYRE) is fairly quiet with 1 mentions across 1 tracked subreddits. The tone is 0% bullish with rising 3-day activity momentum, suggesting building attention.
There is not enough tracked discussion on Spyre Therapeutics (SYRE) to call it either way. The last 7 days carry 6 tracked mentions across 3 sources, under the 10-mention floor Adanos needs before it reads a direction. On the professional side, 17 of 17 analysts rate SYRE a buy.
Of the 17 analysts covering Spyre Therapeutics (SYRE), 17 rate it a buy, 0 a hold and 0 a sell, for a strong buy consensus. The average price target is $103.93. That puts the street ahead of the crowd, which averages 28% bullish.
Spyre Therapeutics (SYRE) does not carry enough tracked discussion this week to have a readable sentiment. 6 mentions across 3 sources is under the 10-mention floor, so the signal stays neutral at 40/100 conviction.
Not for a reason found in the sentiment itself. Spyre Therapeutics (SYRE) drew 6 tracked mentions in the last 7 days, too small a sample to read a direction from, so Adanos holds the signal neutral instead of calling a buy or sell off it.
X is the dominant discussion channel with 3 mentions (50% of total volume). News contributes 2 mentions and Reddit contributes 1 mention. There is too little of it to read a sentiment direction from, while reddit and x and news show rising 3-day activity.
The Adanos signal blends bullish ratio, buzz score, source breadth and 3-day activity momentum into a single buy/sell reading. SYRE's hold signal at 40/100 conviction reflects a sample too thin to read a direction from. It is a research shortcut, not financial advice.
The SYRE sentiment page is regenerated from the latest 7-day tracking window at each build. Data reflects the most recent Reddit posts, tweets and news articles available in the current publishing cycle.
These stocks share a comparable sentiment profile to Spyre Therapeutics with similar bullish ratios, signal direction and discussion volume. All 6 peers carry hold signals, pointing to broad mixed pressure rather than an SYRE-specific issue.
Every data point on this page comes from the Adanos sentiment APIs. Get a free API key and start querying Reddit, X, News and Polymarket sentiment programmatically.
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