NASDAQ: SYRE · Biotechnology

Spyre Therapeutics (SYRE) stock sentiment

Over the past week, Spyre Therapeutics (SYRE) racked up 9 mentions across Reddit, X and news, and the read is an Adanos Hold. That is too little tracked discussion to read a direction from, so the signal stays neutral. Wall Street is more constructive, with 16 of 17 analysts rating SYRE a buy.

Tracked discussion on SYRE is too thin this week to read a direction from, which is why it reads as a Hold.

Wall Street vs the crowd on SYRE

Wall Street’s 94% buy share sits next to a crowd that ranges from Reddit at 0% to X at 100%. No other tracker puts the two side by side.

Analyst ratings

Strong Buy
Buy 16
Hold 1
Sell 0
Avg target $120.08

17 analysts have weighed in: a Strong Buy consensus: 16 buy calls against 0 sell, with an average 12-month price target of $120.08.

17 analysts94% buy share

Crowd sentiment

Hold
Crowd bullish 57%
Spread 100 pts
Most bullish X 100%
Most bearish Reddit 0%

The Adanos signal blends each source’s bullish ratio, source breadth, buzz intensity and 3-day momentum. This week SYRE carries too few tracked mentions to weigh any of them, so the read is Hold rather than a clear buy or sell.

3 sourcesWide divergence

Who is bullish on SYRE

100pt spread
Wall St
94%
X
100%
News
71%
Reddit
0%
Wall Street (analyst buy share)Crowd average 57%

Analysts sit 37 points above the crowd average of 57%, the professionals are more constructive than retail. The split is inside the crowd: X reads 100% bullish while Reddit sits at 0%, a 100-point spread that single-source trackers miss.

Why SYRE reads Hold

Hold 0.0
Bullish Average
Average sentiment is 57.0% bullish, above the 50% neutral line.
+9.1
Trend
More sources are improving than weakening: 1 up, 0 down, 2 flat.
+2.3
Buzz
Discussion intensity is 21.3, well below the usual midpoint.
-2.0
Source Breadth
This signal is based on 3 tracked sources.
+1.5
Consensus
2 bullish sources and 1 bearish source keep the score from getting a consensus bonus.
0.0
This window holds fewer than 10 tracked mentions, too small a sample to carry a buy or sell reading, so the contributions above are set aside and the score is held at zero.

Spyre Therapeutics (SYRE) buzz score vs. EOD price

Over the 30-day window, Spyre Therapeutics (SYRE) buzz held subdued around 34.3 while the price drifted down 11.0% across the period. The chart tracks how social and news attention moved against end-of-day price. Average daily trading volume across the displayed trading days is 1.1M shares. Over the last 7 trading days, SYRE gained 4.1%. Buzz activity in the recent week averaged 29.8 and was relatively stable, swinging between 23.1 and 38.8. Recent volume is in line with the 30-day average, reflecting steady institutional and retail participation. Daily crowd sentiment leaned bullish on 8 of the 16 days with directional mentions, shown as the green, grey and red breakdown bars below the chart.

How each source saw SYRE this week

Signal metrics use the latest 7 days; contributor and breadth context uses the 30-day chart window.

Reddit 7-day signal

Open source page
Buzz 0.0
Bullish 0%
Mentions 0
Trend Stable
4 subreddits · 30-day context7-day sentiment 0.0
Bullish 0%Neutral 100%Bearish 0%
r/technicalanalysis Neutral
Loudest Reddit venue in the 30-day context window with 2 mentions.

X 7-day signal

Open source page
Buzz 36.6
Bullish 100%
Mentions 2
Trend Stable
2 tweets7-day sentiment +0.5
Bullish 100%Neutral 0%Bearish 0%
@Biotech2k1 · 30-day context Bullish 0.29
“When I look for names in biotech, I see a list of top companies in the $XBI that clearly seem like over bubbly tulip mania. Names like $RVM…”
♥ 17↻ 1👁 4K views

News 7-day signal

Open source page
Buzz 27.2
Bullish 71%
Mentions 7
Trend Rising
13 publishers · 30-day context7-day sentiment +0.3
Bullish 71%Neutral 29%Bearish 0%
Insider Monkey · 30-day context Bullish 0.27
“Spyre Therapeutics, Inc. (NASDAQ: SYRE ) reported September 8 results from 44 patients with moderately to severely active ulcerative coliti…” Led by MarketBeat and Nasdaq.

Polymarket signal

No Polymarket data for this stock this week.

Finance Sentiment CLI

Query sentiment for SYRE and 2001+ stocks from your terminal. Filter by source, timeframe and signal strength.

View CLI

Webmaster Widgets

Embed live SYRE sentiment on your own site with drop-in web components.

View Widgets

Spyre Therapeutics (SYRE) at a glance

This week’s sentiment from Adanos, with fundamentals and analyst consensus. A quick-reference snapshot for Sep 11, 2026.

Adanos signalHold
Analyst consensusStrong Buy (16 / 1 / 0)
Crowd bullish (7d)57%
Avg price target$120.08
Most bullish sourceX, 100%
Most bearish sourceReddit, 0%
Sentiment spread100 pts
Mentions (7d)9
Market cap$7.82B
EPS · Beta-$1.96 · 3.0
IndustryBiotechnology

Spyre Therapeutics (SYRE) stock sentiment FAQ

Is Spyre Therapeutics (SYRE) a buy or sell right now?

Adanos will not call Spyre Therapeutics (SYRE) either way right now. The last 7 days carry 9 tracked mentions across 3 sources, under the 10-mention floor, so the signal sits at a neutral hold with 40/100 conviction. This is a sentiment-based reading, not financial advice.

What does Reddit say about SYRE stock?

Reddit discussion around Spyre Therapeutics (SYRE) is fairly quiet with 0 mentions over the last 7 days; the 30-day context spans 4 tracked subreddits. The 7-day tone is 0% bullish; 3-day activity momentum is stable, suggesting steady attention.

Is Spyre Therapeutics (SYRE) bullish or bearish right now?

There is not enough tracked discussion on Spyre Therapeutics (SYRE) to call it either way. The last 7 days carry 9 tracked mentions across 3 sources, under the 10-mention floor Adanos needs before it reads a direction. On the professional side, 16 of 17 analysts rate SYRE a buy.

What do analysts say about Spyre Therapeutics (SYRE)?

Of the 17 analysts covering Spyre Therapeutics (SYRE), 16 rate it a buy, 1 a hold and 0 a sell, for a strong buy consensus. The average price target is $120.08. That puts the street ahead of the crowd, which averages 57% bullish.

What is the sentiment on SYRE stock?

Spyre Therapeutics (SYRE) does not carry enough tracked discussion this week to have a readable sentiment. 9 mentions across 3 sources is under the 10-mention floor, so the signal stays neutral at 40/100 conviction.

Why does SYRE carry a hold signal right now?

Not for a reason found in the sentiment itself. Spyre Therapeutics (SYRE) drew 9 tracked mentions in the last 7 days, too small a sample to read a direction from, so Adanos holds the signal neutral instead of calling a buy or sell off it.

What is driving Spyre Therapeutics (SYRE) sentiment right now?

News is the dominant discussion channel with 7 mentions (78% of total volume). X contributes 2 mentions. There is too little of it to read a sentiment direction from, while news is the only source with rising 3-day activity.

What does the Adanos hold signal mean for Spyre Therapeutics (SYRE)?

The Adanos signal blends bullish ratio, buzz score, source breadth and 3-day activity momentum into a single buy/sell reading. SYRE's hold signal at 40/100 conviction reflects a sample too thin to read a direction from. It is a research shortcut, not financial advice.

How fresh is this SYRE sentiment data?

The SYRE sentiment page is regenerated from the latest 7-day tracking window at each build. Data reflects the most recent Reddit posts, tweets and news articles available in the current publishing cycle.

Peers are ranked first by matching the Hold signal, then by the closest bullish ratio. Discussion activity breaks any remaining ties.

Explore nearby tickers

Access the sentiment APIs behind this page

Every data point on this page comes from the Adanos sentiment APIs. Get a free API key and start querying Reddit, X, News and Polymarket sentiment programmatically.

Get Free API Key