Analyst ratings
24 analysts have weighed in: a Strong Buy consensus: 19 buy calls against 0 sell, with an average 12-month price target of $83.64.
NASDAQ: IONS · Biotechnology
Over the past week, Ionis Pharmaceuticals (IONS) saw 16 mentions across Reddit, X and news, and the read is an Adanos Sell. The crowd averages 42% bullish but is at odds: News runs 58% bullish while X sits at just 25%. Wall Street is more constructive, with 19 of 24 analysts rating IONS a buy.
There is little buzz around IONS this week and little agreement on direction, which is why it reads as a Sell.
Wall Street’s 79% buy share sits next to a crowd that ranges from X at 25% to News at 58%. No other tracker puts the two side by side.
24 analysts have weighed in: a Strong Buy consensus: 19 buy calls against 0 sell, with an average 12-month price target of $83.64.
The Adanos signal blends each source’s bullish ratio, source breadth, buzz intensity and 3-day momentum. This week bullish sits just below the neutral line, momentum is mixed and the 2 sources disagree sharply, so the read is a Sell.
Analysts sit 37 points above the crowd average of 42%, the professionals are more constructive than retail. The split is inside the crowd: News reads 58% bullish while X sits at 25%, a 33-point spread that single-source trackers miss.
Over the 30-day window, Ionis Pharmaceuticals (IONS) buzz held subdued around 22.2 while the price drifted down 27.1% across the period. The chart tracks how social and news attention moved against end-of-day price. Average daily trading volume across the displayed trading days is 4.5M shares. Updated Sep 26, 2026. Over the last 7 trading days, IONS lost 4.8%. Buzz activity in the recent week averaged 27.7 and was variable, swinging between 6.8 and 44.6. Recent volume is running above the 30-day average, suggesting heightened trading interest. Daily crowd sentiment leaned bullish on 12 of the 18 days with directional mentions, shown as the green, grey and red breakdown bars below the chart.
Signal metrics use the latest 7 days; contributor and breadth context uses the 30-day chart window.
No Reddit data for this stock this week.
No Polymarket data for this stock this week.
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View WidgetsThis week’s sentiment from Adanos, with fundamentals and analyst consensus. A quick-reference snapshot for Sep 26, 2026.
| Adanos signal | Sell |
|---|---|
| Analyst consensus | Strong Buy (19 / 5 / 0) |
| Crowd bullish (7d) | 42% |
| Avg price target | $83.64 |
| Most bullish source | News, 58% |
| Most bearish source | X, 25% |
| Sentiment spread | 33 pts |
| Mentions (7d) | 16 |
| Market cap | $7.28B |
| P/E · Forward P/E | n/a · 90.9 |
| EPS · Beta | -$3.47 · 0.4 |
| Revenue (TTM) | $874.1M · -65% margin |
| Industry | Biotechnology |
Based on aggregated sentiment from X and News sources, Ionis Pharmaceuticals (IONS) currently carries an Adanos sell signal with 85/100 conviction. The current cross-source average reads 42% bullish across 2 active sources. Those sources contribute 16 tracked mentions over the last 7 days. This is a sentiment-based reading, not financial advice.
The crowd reads bearish on Ionis Pharmaceuticals (IONS), averaging 42% bullish across 2 tracked sources over the last 7 days. The two ends of the range are News at 58% bullish and X at 25%, a 33-point spread. On the professional side, 19 of 24 analysts rate IONS a buy.
Of the 24 analysts covering Ionis Pharmaceuticals (IONS), 19 rate it a buy, 5 a hold and 0 a sell, for a strong buy consensus. The average price target is $83.64. That puts the street ahead of the crowd, which averages 42% bullish.
Ionis Pharmaceuticals (IONS)'s cross-source average is bearish at 42% bullish. Source readings are split: 1 source leans bullish and 1 source leans bearish. News reads 58% bullish and x coverage is the most negative at 25% bullish. The combined signal points to broad sell-side pressure with 85/100 conviction.
The cross-source average is bearish for Ionis Pharmaceuticals (IONS) at 42% bullish. Source readings are split: 1 source leans bullish and 1 source leans bearish. The most bearish reading is x at 25% bullish. 3-day activity momentum is falling on News, while x activity is rising. The sell signal carries 85/100 conviction.
News is the dominant discussion channel with 12 mentions (75% of total volume). X contributes 4 mentions. The cross-source average is bearish at 42% bullish, while x is the only source with rising 3-day activity. Source readings are split: 1 source leans bullish and 1 source leans bearish.
The Adanos signal blends bullish ratio, buzz score, source breadth and 3-day activity momentum into a single buy/sell reading. IONS's sell signal at 85/100 conviction reflects a bearish cross-source average at 42% bullish. Source readings are split: 1 source leans bullish and 1 source leans bearish. It is a research shortcut, not financial advice.
The IONS sentiment page is regenerated from the latest 7-day tracking window at each build. Data reflects the most recent Reddit posts, tweets and news articles available in the current publishing cycle.
Peers are ranked first by matching the Sell signal, then by the closest bullish ratio. Discussion activity breaks any remaining ties.
Every data point on this page comes from the Adanos sentiment APIs. Get a free API key and start querying Reddit, X, News and Polymarket sentiment programmatically.
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